姓名: | 潘建平 |
職務: | PI |
職稱: | 教授 |
學歷: | 博士研究生 |
專業(yè): | 免疫學/病原生物學 |
所屬院系: | 基礎醫(yī)學系 |
研究方向: | 感染免疫學 |
電話: | 0571-88206896 |
信箱: | jppan@zju.edu.cn |
個人簡介
浙江大學醫(yī)學部病原生物學系副主任、免疫學教授、博士研究生導師,中國免疫學會理事,浙江省免疫學會感染免疫專業(yè)委員會主任委員quanxiangyun.cn,浙江省抗癌協(xié)會腫瘤生物治療委員會委員兼秘書,“International Journal of Cancer”、“Vaccine”等期刊審稿人。
主要研究方向:腫瘤免疫學,黏膜抗感染免疫的細胞和分子機制
在研科主要研項目:不同亞群PP-DC在B細胞向腸黏膜歸巢和IgA產(chǎn)生中的作用及其機制(國家自然科學基金,30872325)
發(fā)表的主要論文:
1.Lu J, Zheng MH, Yan J, Chen YP, Pan J. Effects of vasoactive intestinal peptide on phenotypic and functional maturation of dendritic cells. Inter Immunopharmacol 2008; 8:1449-1454.
2.Pan J, Jin P, Yan J, Kabelitz D. Anti-angiogenic active immunotherapy: a new approach to cancer treatment. Cancer Immunol Immunother 2008; 57:1105-1114.
3.Weng Y, Sun J, Wu Q, Pan J. Regulatory effects of vasoactive intestinal peptide on the migration of mature dendritic cells. J Neuroimmunol 2007; 182: 48-54.
4.Shao P, Zhao LH, Chen Z, Pan J. Regulation on maturation and function of dendritic cells by Astragalus mongholicus polysaccharides. Inter Immunopharmacol 2006; 6: 1161-1166.quanxiangyun.cn
5.Pan J, Heiser A, Maret M, Steinmann J, Kabelitz D. Enhanced anti-metastatic effect of fetal liver kinase 1 and interferon-gamma fusion gene-modified dendritic cell vaccination. Gene Ther 2005; 12:742-750.
6.Pan J, Zhang M, Wang J, Wang Q, Xia D, Sun W, Zhang L, Yu H, Cao X. Intratumoral injection of interferon-gamma gene-modified dendritic cells elicits potent antitumor effects: effective induction of tumor-specific CD8+ CTL response. J Cancer Res Clin Oncol 2005; 131:468-478.
7.Pan J, Zhang M, Wang J, Wang Q, Xia D, Sun W, Zhang L, Yu H, Liu Y, Cao X. Interferon-gamma is an autocrine mediator for dendritic cell maturation. Immunol Lett. 2004; 94 : 141-151.
8.Pan J, Ju DW, Wang Q, Zhang M, Xia D, Zhang L, Yu H, Cao X. Dexamethosone inhibits the antigen presentation of dendritic cells in MHC class II pathway. Immunol Lett 2001; 76 (3): 153-161.
9.Zhang LH,Pan JP,Yao HP, et al. Intrasplenic transplantation of IL-18 gene-modified hepatocytes: an effective approach to reverse hepatic fibrosis in schistosomiasis through induction of dominant Th1 response. Gene Ther 2001; 8: 1333-1342.